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Nexium (Esomeprazole)

A pharmacist explains how Nexium works, why doctors prescribe this acid reflux medication, and common side effects of the drug.Watch More Health ...

Nexium - News


AstraZeneca in deal with generic drugs maker
Times Online - Mar 12, 2010
AstraZeneca in deal with generic drugs maker They include its three biggest sellers: Nexium, an ulcer treatment; Seroquel, an antipsychotic; and Crestor, an anticholesterol drug.

AstraZeneca Will Excercise First Option In Merck JV
Wall Street Journal - Mar 01, 2010
AstraZeneca Will Excercise First Option In Merck JV -AstraZeneca's consummation of the second option will end the contingent payments in respect of Prilosec and Nexium and will effectively end AstraZeneca's

FDA warning: some patients cannot process Plavix
The Associated Press - Mar 12, 2010
In November, the FDA warned that taking stomach-soothing drugs like Prilosec and Nexium alongside Plavix could cut the blood-thinner's effect in half.

AstraZeneca Sues Sun to Block Generic of Nexium IV
BusinessWeek - Mar 03, 2010
Sun is seeking US Food and Drug Administration approval to sell Nexium in a form that is delivered through intravenous injections.

AstraZeneca Sues Sun Pharma For Patent Infringement
Pharmaceutical Business Review - Mar 09, 2010
US FDA approved Nexium (Esomeprazole Magnesium) in 2005. Its patents are valid in the US till 2014. Nexium is said to be the largest selling drug for

Does heartburn lead to cancer?
Herald & Review - Mar 09, 2010
I tried taking a generic version of Nexium, but it did not help at all. A second doctor advised me not to take drugs, since they didn't help.

Money Briefs
Worcester Telegram - Mar 04, 2010
Sun is seeking US Food and Drug Administration approval to sell Nexium in a form that is delivered through intravenous injections.

Gastrointestinal Directory

Nexium
From AstraZeneca. Used to treat heartburn symptoms and erosions of the esophagus caused by acid reflux.

Nexium Information from Drugs.com
Nexium (esomeprazole) is used to treat GERD and other conditions involving excessive stomach acid. Includes Nexium side effects, interactions, and indications.

Nexium (Esomeprazole Magnesium) Drug Information: Uses, Side ...
Learn about the prescription medication Nexium (Esomeprazole Magnesium), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.

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AstraZeneca in deal with generic drugs maker

12.03.10

Patents on seven AstraZeneca drugs will expire in the next four years. They include its three biggest-sellers: Nexium, an ulcer treatment; Seroquel, an antipsychotic; and Crestor, an anticholesterol drug. The company said last month that this may lead to “a period of fluctuating earnings”.

AstraZeneca wants to boost sales in emerging markets to 25 per cent of annual revenue by 2014, from 13 per cent last year – in part to minimise the impact of patent losses. It will hold an investor day on March 16 to highlight its plans for emerging markets.

AstraZeneca already sells some of its own medicines in emerging markets as branded generics. Crestor, its cholesterol drug, is priced to compete with a range of cheap copies in India, where it has no patent protection.

Emerging markets tie-ups

• GlaxoSmithKline struck a deal with Dr Reddy’s of India last June, and has bought 16 per cent of Aspen in South Africa.

Source: Times Online

FDA warning: some patients cannot process Plavix

12.03.10

WASHINGTON — The Food and Drug Administration is adding its strongest warning to the label for Plavix after reports that some patients cannot process the blockbuster blood thinner.

The FDA said in a statement Friday that certain patients with a genetic variation cannot metabolize the drug, putting them at increased risk for heart attack and stroke.

Patients can determine if they don't respond to Plavix by taking a genetic test. The FDA recommends non-responders use other blood thinners, such as aspirin.

The FDA previously added similar language to Plavix's label, but the new warning appears within a black box, the FDA's most severe safety warning.

Plavix is prescribed to heart disease patients to prevent dangerous blood clots, which can cause heart attack, stroke and death.

In order to work effectively, Plavix must be broken down by a particular liver enzyme. But FDA says 2 to 14 percent of people in the U.S. have low levels of the enzyme, preventing them from successfully processing Plavix. The likelihood of being a non-responder varies by race, according to the FDA.

Source: The Associated Press

AstraZeneca Sues Sun to Block Generic of Nexium IV

03.03.10

(Adds use for Nexium IV in fourth paragraph.)

By Susan Decker

March 3 (Bloomberg) -- AstraZeneca Plc, the U.K.’s second- biggest drugmaker, sued India’s Sun Pharmaceuticals Industries Ltd. to prevent it from selling a generic form of the ulcer medicine Nexium IV in the U.S. before 2014.

Sun is seeking U.S. Food and Drug Administration approval to sell Nexium in a form that is delivered through intravenous injections. AstraZeneca claims the generic copy would infringe two patents that expire in May 2014 and November 2014.

Nexium IV, first approved by regulators in 2005, is similar to the “purple pill” that is most commonly sold as a capsule. Nexium in all forms generated $2.84 billion in U.S. sales last year for the London-based company, AstraZeneca said Jan. 28. Global Nexium sales were $4.96 billion, making it AstraZeneca’s biggest seller.

Nexium IV is a small part of sales and is typically given while people are in the hospital through an intravenous drip, said Blair Hains, a spokesman for the company. He said the company doesn’t break out sales of Nexium IV.

Source: BusinessWeek