Lilly criticized for new Evista ads. - Financial Advertising

"This is about educating those women about the additional benefit this drug has to offer," said Deirdre Ibsen, Lilly's director of osteoporosis marketing. "That will obviously translate into something more (in sales) for Evista. What it is at this point, we don't know Don't know (DK, DKed)"Don't know the trade." A Street expression used whenever one party lacks knowledge of a trade or receives conflicting instructions from the other party. ." But some breast-cancer advocacy groups take issue with the ads. They say Evista's risks are too great for healthy women to consider using.

 such as "Good Housekeeping Good Housekeeping is a women's magazine owned by the Hearst Corporation, featuring articles about women's interests, product testing by The Good Housekeeping Institute, recipes, diet, health as well as literary articles. ." The company said the new ads are not a broad-market push, but are targeted at a fairly narrow market of postmenopausal women who have osteoporosis.

"This is about educating those women about the additional benefit this drug has to offer," said Deirdre Ibsen, Lilly's director of osteoporosis marketing. "That will obviously translate into something more (in sales) for Evista. What it is at this point, we don't know Don't know (DK, DKed)"Don't know the trade." A Street expression used whenever one party lacks knowledge of a trade or receives conflicting instructions from the other party. ." But some breast-cancer advocacy groups take issue with the ads. They say Evista's risks are too great for healthy women to consider using.

They say only a small percentage of women might avoid breast cancer by taking a drug like Evista. "This is not the approach we should be taking," said Brenda Salgado, program manager of Breast Cancer Awareness in San Francisco. "We believe that any pill powerful enough to lower the incidence of breast cancer will most certainly cause other health problems and diseases. Why should we substitute one problem for another?" Carolina Hinestrosa, executive vice president of the National Breast Cancer Coalition The National Breast Cancer Coalition (NBCC) is a grassroots membership organization, comprised of hundreds of member organizations and tens of thousands of individuals dedicated to ending breast cancer through action and advocacy.  in Washington, said many women who take Evista will not need it and won't benefit from it. "Yet there are many vulnerable women who are afraid of breast cancer," she said.

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Evista - News


Lilly moves target ethics, compliance
The company also had improperly marketed Evista, its osteoporosis drug, and Prozac, its antidepressant. In response, several shareholders sued the company,

Pfizer osteoporosis drug gets lukewarm review
N) and sold under the brand name Evista. Last month, the US Food and Drug Administration asked for additional information from Pfizer Inc (PFE.

Teva moves closer to generic Evista sales in Europe
TASE: TEVA) is a step closer to marketing a generic version of osteoporosis drug Evista (Raloxifene) in Europe. In September, a US court ruled against

Boning Up on Pfizer's Drug
The drug reduced the risk of both spinal and non-spinal fractures, but it doesn't appear to work any better than Eli Lilly's (NYSE: LLY) Evista,

Letter: Available cancer drugs are not being used
Prostate cancer is not unique, Scientists have what they consider definitive evidence that two drugs, Tamoxifen and Raloxifene, or Evista, can cut the risk

Approaching Support- Eli Lilly
Some of the company's patents include Zyprexa, Prozac, Permax, Humulin, Evista, Humalog, Humatrope, Vancocin, Keflex, Nebcin , Lorabid, Gemzar, Tylan,

NICE osteoporosis guidance survives legal challenge
The guidance on secondary fracture prevention follows the same principles, with the addition of raloxifene (Evista) and teriparatide (Forsteo) as possible

Womens Health Directory

Evista (Raloxifene)
Information about the drug from Eli Lilly that is used for prevention and treatment of osteoporosis in women past menopause. .

Evista (Raloxifene) Drug Information: Uses, Side Effects ...
Learn about the prescription medication Evista (Raloxifene), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.

EVISTA® (raloxifene HCl) | Info for Healthcare Professionals
EVISTA is indicated for the treatment of osteoporosis and for the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis. ...

Evista Information from Drugs.com
Evista (raloxifene) is used to treat and prevent osteoporosis in postmenopausal women. Includes Evista side effects, interactions and indications.

EVISTA
Read the Medication Guide that comes with EVISTA before you start taking it and each time ... your doctor about EVISTA when you start taking it and at regular checkups. ...

Letter: Available cancer drugs are not being used

I found this article by Gina Kolata in the New York Times and hope it will be of interest.

“Many Americans do not think twice taking medicines to prevent heart disease and stroke. But cancer is different. The few medicines proved to deter cancer are wildly ignored.

“Take prostate cancer. More than 192,000 cases of it will be diagnosed this year, and more than 27,000 men will die from it.

“A large and rigorous study found that a generic drug, Finasteride, costing about $2 a day, could prevent as many as 50,000 cases each year. Another study found that a close cousin, Dutasteride, about $3.50 a day, has the same effect. These drugs are largely ignored.

“As the response to the prostate drugs shows, people are not enthusiastic about taking anti-cancer pills. Others are just unaware of them. Prostate cancer is not unique, Scientists have what they consider definitive evidence that two drugs, Tamoxifen and Raloxifene, or Evista, can cut the risk of breast cancer in half. Women and doctors have pretty much ignored the findings.

Generic Evista Approved for Sale in Europe

Lilly has stated 2009 global sales for Evista were slightly more than $1 billion.

Teva's efforts to sell its version in the U.S. before Lilly's patent expires was blocked last year by a court.

The Israeli company is appealing that ruling which maintains protection for Evista in the U.S. until 2014.


Press Release

LONDON, Feb. 18, 2010 -- On 18 February 2010 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Raloxifene Teva 60 mg Film-coated Tablets intended for treatment and prevention of osteoporosis in postmenopausal women. A significant reduction in the incidence of vertebral, but not hip fractures has been demonstrated. The applicant for this medicinal product is Teva Pharma B.V. They may request a re-examination of any CHMP opinion, provided they notify the European Medicines Agency in writing of their intention within 15 days of receipt of the opinion.

Pfizer Experimental Bone Drug Shows Mixed Results In Study

By Jonathan D. Rockoff

Last we heard of Fablyn, an experimental bone drug for the treatment of postmenopausal women, U.S. regulators were holding off on approval after FDA staff and outside reviewers raised concerns and Pfizer, the pill’s maker, was shopping it around to other companies.

Today’s New England Journal of Medicine reports that the drug met the goals of a key study. Fablyn prevented certain fractures in postmenopausal women and reduced the risk of breast cancer, said the study, sponsored by Pfizer. However, the drug didn’t show a statistically significant benefit preventing debilitating hip fractures. Also, it increased the risk of blood clots by two times.

The Phase 3 study looked at 8,556 women between the ages 59 and 80 over five years. Its mixed results aren’t likely to clarify Fablyn’s future. Here’s a Reuters account of the findings.

The study’s lead author, Steven Cummings of the California Pacific Medical Center Research Institute, said the results show Fablyn’s effectiveness as a second-line treatment for certain postmenopausal women. The drug would be a candidate, he said, for those women coping with osteoporosis who are at high risk of breast cancer but not for spine fractures, which other osteoporosis therapies treat more effectively.